Nature: raw material
Color: white powder
Material: powder
Function: Reduce weight and body weight
Minimum order quantity: negotiable
Payment terms: Bank Transfer, Wise, PayPal, Western Union, Bitcoin and USDT
Supply capacity: 1000000 kg/week
Delivery period: within 24 hours
Regular package: 1kg/package, as your request
Categories: Cagrilintide
Tirzepatide is a dual GIP and GLP-1 receptor agonist, mimicking the effects of endogenous GIP while inducing cAMP synthesis at the GLP-1 receptor. Tirzepatide is a potent instrument for controlling both weight and blood sugar, thanks to its dual GLP-1/GLP action. Researchers have found that its dual receptor agonism produces a synergistic effect for significantly enhanced insulin response and glucagonostatic activity, versus administering either GIP or GLP-1 monotherapy.
GIP and GLP-1 are the two primary incretin hormones that the intestine secretes upon ingestion of glucose or nutrients, with the effect of stimulating insulin secretion from pancreatic beta cells. Tirzepatide has similar affinity at the GIP receptor as native GIP, but has five times lower GLP-1 receptor affinity compared to native GLP-1. In the latter, tirzepatide has a preference for cAMP signaling over beta-arrestin recruitment.
This biased agonism of tirzapetide and unique GLP-1 signaling are believed to underlie its efficacy in enhancing insulin secretion. In fact, clinical trials have demonstrated tirzepatide’s superior efficacy and comparable safety as a glucose lowering agent when compared to established T2D treatments.
Researchers should also note tirzepatide’s ability to significantly increase adiponectin, an adipokine linked to lipid and glucose metabolism regulation. Increases of serum adiponectin have been associated with weight loss, exercise, and improved nutrition. Researchers believe that this particular mechanism of tirzepatide has cardioprotective implications.
Company slogan: Innovation, Cooperation, Win Win
Company Introduction: Zhengzhou Longjia Electronic Technology Co., Ltd. is a professional pharmaceutical technology company dedicated to the research and development, production, and sales of peptides, pharmaceutical raw materials, pharmaceutical intermediates, and fine chemical intermediates.
Company team: Zhengzhou Longjia Electronic Technology Co., Ltd. has a strong technical background, and the team members are all doctoral, master's, and undergraduate students. They are skilled in process route design, synthesis, process optimization, and new drug research for drugs and chemical intermediates. At the same time, the company is equipped with various advanced HPLC-MS, GC-MS instruments and organic synthesis detection equipment, which can meet the detection needs from milligrams to kilograms.
Company slogan: Innovation, Cooperation, Win Win
Company Introduction: Zhengzhou Longjia Electronic Technology Co., Ltd. is a professional pharmaceutical technology company dedicated to the research and development, production, and sales of peptides, pharmaceutical raw materials, pharmaceutical intermediates, and fine chemical intermediates.
Company team: Zhengzhou Longjia Electronic Technology Co., Ltd. has a strong technical background, and the team members are all doctoral, master's, and undergraduate students. They are skilled in process route design, synthesis, process optimization, and new drug research for drugs and chemical intermediates. At the same time, the company is equipped with various advanced HPLC-MS, GC-MS instruments and organic synthesis detection equipment, which can meet the detection needs from milligrams to kilograms.
In the future, the company will continue to be committed to "doing fine, specialized and stronger", and strive to build an advanced professional manufacturing base in the industry.
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